HOUSTON — Andre Johnson caught a screen pass from Matt Schaub and ran 48 yards for the winning touchdown in overtime as the Houston Texans rallied to beat Jacksonville 43-37 on Sunday.
Schaub threw a career-high five touchdown passes, completed a franchise-record 43 passes and finished with 527 yards passing, second most in NFL history. Warren Moon also threw for 527 yards for the Houston Oilers in December 1990 against Kansas City.
Norm Van Brocklin holds the record with 554 for the Rams in 1951.
Johnson caught 14 passes for 273 yards, both career highs. The Texans (9-1) won an overtime game for the first time at Reliant Stadium.
Chad Henne threw a career-high four touchdown passes in relief of injured Blaine Gabbert for the Jaguars (1-9). Rookie Justin Blackmon had 236 yards receiving.
Falcons 23, Cardinals 19
At Atlanta, Matt Ryan overcame a career-worst five interceptions, guiding Atlanta to its only offensive touchdown in the fourth quarter in a sloppy win.
The Falcons (9-1) turned it over a total of six times, but Michael Turner scored on a 1-yard run with 6:40 remaining to give Atlanta its first lead of the game. Ryan set up the score with four completions for 64 yards, including a 9-yarder to Tony Gonzalez on third-and-5 at the Arizona 10.
Coming off a bye, Arizona (4-6) lost its sixth straight game. The Cardinals tried to bolster their anemic offense by switching quarterbacks, replacing John Skelton with rookie Ryan Lindley, but Larry Fitzgerald couldn't hang on to a fourth-down pass after Ryan's fifth pick.
Packers 24, Lions 20
At Detroit, Aaron Rodgers threw two touchdown passes, including a 22-yarder to Randall Cobb with 1:55 left to lift Green Bay.
Mason Crosby made a 39-yard field goal with 19 seconds to go after missing two field goals earlier in the game.
Matthew Stafford couldn't put the Lions ahead on either of their last two drives in a game he'd like to forget.
Cowboys 23, Browns 20, OT
At Arlington, Texas, Dan Bailey kicked a 38-yard field goal in overtime and Dallas overcame a critical fumble by Tony Romo that sparked a wild ending.
Bailey's winning kick with 6:07 remaining in OT came after both teams punted once in the first overtime game at Cowboys Stadium. Bailey hit a tying 32-yard field goal with 2 seconds left in regulation.
Dallas (5-5) rallied from a 13-0 halftime deficit and went ahead 17-13 on Romo's 28-yard pass to Dez Bryant.
Buccaneers 27, Panthers 21, OT
At Charlotte, N.C., Josh Freeman threw a 15-yard touchdown pass to Dallas Clark in overtime to cap a comeback.
It was Freeman's third touchdown pass of the game for the Buccaneers (6-4).
Carolina appeared to have the game in hand after a 29-yard touchdown pass from Cam Newton to Brandon LaFell put the Panthers (2-8) up 21-10 with 4:34 left in the game. But after a 40-yard field goal by Connor Barth, the Panthers were forced to punt, and Freeman led the Bucs 80 yards on seven plays in 50 seconds with no timeouts.
Ravens 13, Steelers 10
At Pittsburgh, Jacoby Jones returned a punt for a touchdown, Justin Tucker kicked two field goals and Baltimore took control of the AFC North with a victory over Pittsburgh.
The Ravens (8-2) moved two games in front of the Steelers (6-4) by shutting down Pittsburgh's offense, which sputtered without injured quarterback Ben Roethlisberger.
Byron Leftwich, making his first start in more than three years, completed 18 of 39 passes for 201 yards and an interception. He ran for a score but was also sacked three times.
Patriots 59, Colts 24
At Foxborough, Mass., the Patriots used three scoring passes from Tom Brady, two touchdowns on interception returns and another on a punt return to match a team single-game scoring record.
he first matchup between three-time Super Bowl winner Brady and star rookie Andrew Luck was no match.
Saints 38, Raiders 17
At Oakland, Calif., Drew Brees threw three touchdown passes and Malcolm Jenkins returned an interception for another score to get the Saints back to .500.
Lance Moore caught two touchdown passes and Mark Ingram ran for a score as the Saints (5-5) won for the fifth time in six games and are in position to make a late-season playoff run despite the season-long distraction from the bounty scandal.
Broncos 30, Chargers 23
At Denver, Peyton Manning threw for three touchdowns and Von Miller had three sacks to take the league lead with 13. Denver took a three-game lead in the AFC West by sweeping the Chargers.
Manning threw for 270 yards. He got off to a slow start, throwing an interception that Eric Weddle returned for a score and an early 7-0 lead. But the Broncos (7-3) took a 10-7 lead early in the second quarter and never trailed again.
Redskins 31, Eagles 6
At Landover, Md., Robert Griffin III threw four touchdown passes, and Washington broke a three-game losing streak.
Griffin completed 14 of 15 passes for 200 yards and also ran 11 times for 85 yards. He threw for scores of 6, 49, 61 and 17 yards — one in each quarter.
Jets 27, Rams 13
At St. Louis, Mark Sanchez directed a turnover-free offense and Bilal Powell ran for the first two touchdowns of his career as the Jets ended a three-game losing streak.
Chaz Schilens scored on a 25-yard reception and Nick Folk kicked a pair of 51-yard field goals for the Jets (4-6), who were outscored 58-16 the previous two games. The Jets overcame a controversial practice week with several anonymous players quoted in a newspaper report disparaging the ability of backup quarterback Tim Tebow, who had a handful of snaps but was no factor.
Bengals 28, Chiefs 6
At Kansas City, Mo., Andy Dalton threw for 230 yards and accounted for three touchdowns and A.J. Green caught a touchdown pass in his ninth straight game.
Green finished with six catches for 91 yards in another dazzling performance, Mohamed Sanu had a scoring grab and BenJarvus Green-Ellis ran for 101 yards and a touchdown as the Bengals (5-5) won their second straight following a four-game losing streak.