INDIANAPOLIS — The Indianapolis Colts made Chuck Pagano a winner in his return to the sideline.
Andrew Luck threw for two touchdowns and Deji Karim swung the game with a 101-yard kickoff return in the third quarter during a 28-16 victory over Houston on Sunday. It was Pagano's first game back as coach since starting treatment for leukemia Sept. 26.
Indianapolis (11-5) heads into the playoffs as the No. 5 seed and on a roll. The Colts will open the postseason next Sunday on the road against the Baltimore Ravens.
Slumping Houston (12-4) is the third seed and will host Cincinnati. The Texans lost three of their last four games, and J.J. Watt failed to break Michael Strahan's single-season sacks record.
Seahawks 20, Rams 13
At Seattle, Russell Wilson tied Peyton Manning's record for most touchdown passes by a rookie with 26, and his 1-yard TD run with 1:39 left allowed Seattle to finish as the only unbeaten team at home.
Chargers 24, Raiders 21
At San Diego, Micheal Spurlock returned the opening kickoff 99 yards for a touchdown on wet, gloomy day in what's expected to be Norv Turner's final game as Chargers coach.
Turner and general manager A.J. Smith are expected to be fired because the Chargers (7-9) missed the playoffs for the third straight season. The Raiders finished 4-12.
Redskins 28, Cowboys 18
At Landover, Md., Robert Griffin III ran for a touchdown, and fellow rookie Alfred Morris rushed for 200 yards and three scores as the Redskins won their first division title in 13 years by beating the Dallas Cowboys.
Bengals 23, Ravens 17
At Cincinnati, Carlos Dunlap returned an interception 14 yards for a touchdown in the fourth quarter.
The Ravens (10-6) had already clinched their second straight AFC North title, and they will open the playoffs at home against Indianapolis.
Broncos 38, Chiefs 3
At Denver, Peyton Manning threw for 304 yards and three touchdowns to lift Denver into the No. 1 seed for the AFC playoffs.
Manning finished the season with 4,659 yards, 41 short of his career high.
Patriots 28, Dolphins 0
At Foxborough, Mass., Tom Brady threw two touchdown passes and New England earned a playoff bye.
Buccaneers 22, Falcons 17
At Atlanta, the Falcons couldn't follow through with their plan to gain momentum for the playoffs as Josh Freeman threw a touchdown pass to Mike Williams and Doug Martin ran for 141 yards.
Bears 26, Lions 24
At Detroit, Jay Cutler threw for 257 yards and a touchdown and helped seal the game with a late scramble. Chicago (10-6) needed a Minnesota loss to Green Bay to reach the postseason, but didn't get it.
Giants 42, Eagles 7
At East Rutherford, N.J., there will be no Super Bowl repeat for the Giants. Not even a playoff berth despite Eli Manning's career-high five touchdown passes.
Steelers 24, Browns 10
At Pittsburgh, Ben Roethlisberger threw three short touchdown passes, and Pittsburgh avoided its first losing season in nearly a decade.
Bills 28, Jets 9
At Orchard Park, N.Y., C.J. Spiller scored on a 66-yard catch and run in helping underachieving Buffalo, while Jets quarterback Mark Sanchez had two more turnovers.
Titans 38, Jaguars 20
At Nashville, Tenn., Tennessee became the first NFL team with two players scoring twice on returns in closing out the season with two wins in its final three games.
Panthers 44, Saints 38
At New Orleans, Drew Brees passed for 396 yards, giving him 5,177 this season. That makes him the first player to eclipse 5,000 yards three times.