SEATTLE — David Ortiz doubled in his first at-bat to become baseball's career leader in hits as a designated hitter and hit a two-run homer an inning later, leading the Boston Red Sox to an 11-4 victory over Seattle on Wednesday.
Ortiz entered the night tied with Harold Baines for the most hits as a DH and it took just one at-bat to claim the record. Ortiz doubled to left-center field to lead off the second inning and was acknowledged by a standing ovation from the mix of Red Sox and Mariners fans.
An inning later, Ortiz collected his eighth hit of the series with a two-run homer off Seattle starter Aaron Harang (4-8), his 19th this season.
Jacoby Ellsbury had three hits to extend his hitting streak to 18 games, currently the best in baseball, and the Red Sox knocked around Harang for seven runs and eight hits.
Felix Doubront (6-3) pitched seven innings, giving up five hits and one run with six strikeouts and two walks.
Tigers 8, White Sox 5
At Detroit, Prince Fielder homered, Rick Porcello pitched six solid innings and the Detroit Tigers bounced back with a victory over the Chicago White Sox.
Detroit allowed 23 hits in an 11-4 loss to the White Sox on Tuesday, but it was the Tigers who did the slugging early on in this game. Fielder lined a two-run shot to right field in the first inning for his 16th homer.
Orioles 6, Rangers 1
At Baltimore, Wei-Yin Chen returned from the disabled list to pitch seven innings of three-hit ball, and the Baltimore Orioles got a three-run homer from Nolan Reimold in a victory over Texas.
Yankees 8, Royals 1
At New York, Robinson Cano hit a three-run homer, Lyle Overbay added a grand slam and the New York Yankees snapped out of their offensive funk with a win over Kansas City.
Blue Jays 5, Indians 4
At Cleveland, Munenori Kawasaki hit a two-run single with the bases loaded in the ninth inning and the Toronto Blue Jays beat Cleveland.
Kawasaki, who broke an 0-for-18 slump, broke a 2-all tie with his two-out hit. A third run scored when center fielder Michael Bourn misplayed the ball for an error.
Rays 4, Twins 3, 13 innings
At St. Petersburg, Fla., Ben Zobrist hit an RBI single with two outs in the 13th inning and Tampa Bay beat Minnesota to win its season-best seventh straight game.
Zobrist lined a 1-2 pitch from Ryan Pressly (2-1) into the gap in right-center field, ending a 4-hour, 47-minute game that featured 35 strikeouts — 19 for Rays pitchers.
Mets 7, Giants 2
At San Francisco, former Giants prospect Zack Wheeler pitched seven sharp innings, Marlon Byrd homered again and the New York Mets completed their first sweep in San Francisco since 1994.
Daniel Murphy and John Buck each had two hits and drove in two runs as the Mets won their fourth in a row, including three straight over the slumping World Series champions. The Giants have lost 16 of 19.
Wheeler (3-1), a former Giants' first-round draft pick, took a shutout into the seventh. He allowed one run and three hits overall, striking out five and walking three.
Matt Cain (5-6) lasted less than an inning for the first time in his career, giving up three runs on two hits while getting just two outs. He walked three.
Nationals 5, Phillies 1
At Philadelphia, Gio Gonzalez tossed seven sharp innings, the Nationals hit a pair of consecutive homers off Cliff Lee and Washington beat the Philadelphia Phillies.
Anthony Rendon and Wilson Ramos hit back-to-back shots off Lee to start the fifth and Ryan Zimmerman and Jayson Werth did it to open the sixth.
Marlins 6, Braves 2
At Miami, Giancarlo Stanton hit a two-run double to end a 10-game RBI drought, and the Miami Marlins broke a five-game losing streak by beating Atlanta 6-2.
Reds 6, Brewers 2
At Milwaukee, Mike Leake scattered four hits over 81/3 innings and Brandon Phillips had three RBI, lifting the Cincinnati Reds over the Milwaukee Brewers.
The Reds put the leadoff runner on base in each of the first seven innings and snapped a three-game losing streak.
Rockies 5, Padres 4
At San Diego, Rockies starter Jorge De La Rosa took a one-hit shutout into the sixth inning and Colorado held on to give the left-hander his sixth straight win against the San Diego Padres.
De La Rosa lifted his record at Petco Park to 3-0 with a 1.88 ERA. His winning streak against San Diego spans eight starts.
Pirates 5, Athletics 0
At Pittsburgh, Francisco Liriano scattered four hits over seven innings, and the Pittsburgh Pirates beat the Oakland Athletics.
Liriano (9-3) struck out six and walked one. He trimmed his ERA to 2.00 as the Pirates snapped a four-game losing streak. Pedro Alvarez went 2 for 4 and drove in two runs for Pittsburgh. Andrew McCutchen, Starling Marte and Jose Tabata also had two hits each as the Pirates beat Oakland for the first time ever.
Cardinals 5, Astros 4
At St. Louis, Matt Carpenter hit a two-run home run and Matt Holliday drove in two with a two-out hit to help the St. Louis Cardinals beat the Houston Astros.
Angels 13, Cubs 2
At Chicago, Josh Hamilton hit two home runs, Albert Pujols also connected and the Los Angeles went deep a season-high five times in a rout of the Chicago Cubs.
Mark Trumbo and Brendan Harris also homered for the Angels. Hamilton drove in five runs and Pujols drove in three.