BOSTON — Stephen Drew singled in the winning run in the 15th inning to lift the Boston Red Sox to a 5-4 victory over the Seattle Mariners and back into first place in the AL East on Wednesday night.
Dustin Pedroia drew a leadoff walk and took second on a groundout by David Ortiz. Mike Napoli was walked intentionally and Jarrod Saltalamacchia struck out. Jonny Gomes then walked, loading the bases, and Drew hit a liner just inside the right-field line as Pedroia scored the decisive run.
Boston moved a half-game ahead of Tampa Bay in the division.
Drew Britton (1-0) pitched two innings for his first major league win. Lucas Luetge (0-2) took the loss.
Seattle's Kyle Seager had tied the game at 4 in the eighth with his 17th homer of the year, a solo shot off Junichi Tazawa.
Pedroia had given the Red Sox a 4-3 lead with a two-run homer in the seventh, his eighth.
Astros 11, Orioles 0
At Baltimore, rookie left-hander Brett Oberholtzer allowed three hits over seven innings to earn his first major league win, Jason Castro hit a grand slam, and Houston routed Baltimore.
Matt Dominguez homered and had a career-high four hits for the Astros, who built a 9-0 lead in the fourth inning and coasted to their most lopsided victory of the season.
Blue Jays 5, Athletics 2,10 innings
At Oakland, Calif., Jose Bautista hit a go-ahead double in the top of the 10th inning, and the Toronto Blue Jays beat the Oakland.
Bautista doubled off Jesse Chavez (2-3). Rookie catcher Stephen Vogt's second costly passed ball of the game allowed Jose Reyes to advance after a leadoff infield single, and Reyes scored on Bautista's hit.
Casey Janssen (4-0) pitched a 1-2-3 ninth for the win, while Brett Cecil finished for his first major league save in two opportunities.
Rangers 2, Angels 1
At Arlington, Texas, Adrian Beltre led off the bottom of the ninth for Texas with a home run to beat the Los Angeles Angels, completing a three-game series sweep in which the Rangers won each on game-ending homers.
Beltre hit his 23rd homer, connecting off Michael Kohn (1-1).
Indians 6, White Sox 5,10 innings
At Cleveland, Carlos Santana's leadoff home run in the 10th inning sent the Cleveland Indians over the Chicago White Sox for their seventh straight win.
Pirates 5, Cardinals 4
At Pittsburgh, Russell Martin drove home Neal Walker with the go-ahead run in the eighth inning and the Pittsburgh Pirates rallied to beat the St. Louis Cardinals.
Martin's sharp grounder off Trevor Rosenthal (1-2) rolled into left field, giving Walker enough time to score from second. The Pirates' fourth straight win over the Cardinals gave Pittsburgh a 21/2;-game lead in the NL Central.
Braves 9, Rockies 0
At Atlanta, Mike Minor allowed only two hits in seven scoreless innings, Brian McCann hit a three-run homer in a seven-run third, and Atlanta beat Colorado for its sixth straight win.
Giants 9, Phillies 2
At Philadelphia, Chad Gaudin threw seven sharp innings, Brett Pill and Brandon Crawford hit homers, and San Francisco snapped a five-game losing streak with the victory over Philadelphia.
The defending World Series champion Giants are last in the NL West. The Phillies entered 111/2; games out of first place and fell to nine back in the wild-card standings.
Gaudin (5-2) allowed one run and four hits, striking out five. He also got his first career RBI on a single that was just his second hit in 59 at-bats.
Reds 4, Padres 1
At San Diego, Homer Bailey came within two outs of a five-hit shutout to end his four-start losing streak and Cincinnati beat San Diego to snap a five-game skid.
Marlins 3, Mets 2
At Miami, Jake Marisnick hit his first major league home run and Henderson Alvarez pitched into the eighth inning to lead Miami over New York.
Cubs 6, Brewers 1
At Chicago, Edwin Jackson pitched eight solid innings, David DeJesus drove in three runs and Chicago beat Milwaukee to salvage the finale of the four-game series.
Tigers 11, Nationals 1
At Detroit, Alex Avila and Torii Hunter hit homers in a five-run second inning and the Detroit Tigers scored five more runs in the fourth inning while routing Washington.
Diamondbacks 7, Rays 0
At St. Petersburg, Fla., Wade Miley pitched two-hit ball into the seventh inning and Eric Chavez drove in three runs, leading the Arizona Diamondbacks over Tampa Bay.
Paul Goldschmidt hit his 24th homer, scored three runs and reached base four times. Cody Ross had three straight hits and drove in two runs as Arizona broke a three-game losing streak.
Yankees 3, Dodgers 0
At Los Angeles, pinch-hitter Lyle Overbay singled in the go-ahead run with two outs in the top of the ninth inning, helping New York to the win.
Overbay singled on a 1-2 pitch from Paco Rodriguez. Robinson Cano scored after reaching on a fielder's choice groundout.
The Yankees added two more runs on an error by Dodgers second baseman Mark Ellis.