TUCSON, Ariz. — There were plenty of injuries to go with the insult on the scoreboard.
No. 5 Oregon lost its starting tailback and two key defensive linemen during Saturday's 42-16 agonizing defeat to Arizona on Saturday at Arizona Stadium.
Byron Marshall suffered an ankle injury on a second-and-goal run in the first quarter. The sophomore appeared to fight his way down to the 1-yard line, but after an official review he was ruled down at the 6.
The Ducks settled for a field goal to make the score 14-3. Marshall's day was done after three carries for 4 yards, which leaves him 5 yards shy of 1,000 for the season.
"When Byron isn't Byron, it's hard," quarterback Marcus Mariota said after a rough day in the red zone where Oregon scored two touchdowns in five trips inside the 20. "He's a great player."
De'Anthony Thomas (16 carries, 83 yards) and Thomas Tyner (11 carries, 53 yards with a lost fumble) tried to pick up the slack, but Mariota attempted 41 passes with Oregon trailing by double digits for over 52 minutes.
Meanwhile, as Arizona star Ka'Deem Carey was piling up 206 yards rushing with four touchdowns, Oregon defensive tackles Wade Keliikipi and Ricky Heimuli went down and hobbled off the field with injuries that kept them out.
"They're big bodies inside, and we'll just have to figure out the next man. That's why we rotate," defensive tackle Taylor Hart, who is playing through a hand injury, said after making nine tackles. "We can just do what we need to do."
Sophomore Alex Balducci (three tackles) and senior Jared Ebert (one tackle) filled in for most of the second half.
"They did their best and they've been practicing in that position," Hart said. "We're just a little banged up. We'll be all right."
Starting linebacker Derrick Malone, who left the Utah game with a shoulder injury, played through the pain and led the Ducks with 12 tackles.
Starting left tackle Tyler Johnstone also returned after spraining an ankle against the Utes. Wide receiver Keanon Lowe, who did not play against Utah, contributed on special teams and finished with two catches for 35 yards.
The good news: Mariota said his injured left knee is healing.
"I definitely feel better," he said. "I'm just going to continue to get healthy."
More bad news: Mariota didn't know if he suffered a concussion after taking a hit following his second interception.
"I'm not too sure; I'll have to talk to the training staff," he said.
LONG WAIT: The Ducks, whose BCS national title dreams were dashed by the 26-20 loss at Stanford on Nov. 7, have now lost consecutive road games for the first time since 2007 when they were beaten at Arizona (Nov. 15) and UCLA (Nov. 24) that season.
Before the Stanford game, Oregon had won 18 consecutive true road games dating back to Nov. 21, 2009.
The Ducks' next road test hasn't been scheduled by the Pac-12 yet. Oregon hosts South Dakota, Wyoming and Michigan State at Autzen Stadium next season before the conference grind begins.
NOTABLE: The 42 points allowed by Oregon were the most by Nick Aliotti's defense since USC scored 51 on Nov. 3, 2012 (a game the Ducks won 62-51). "¦ Oregon actually outgained Arizona 506-482 in total offense but lost the turnover battle 3-0. "¦ Mariota has at least one touchdown pass in all 24 games he has started at Oregon. "¦ The Ducks lead the all-time series 24-15, including an 11-10 mark in Tucson. "¦ Rich Rodriguez improved to 3-6 against ranked teams at Arizona.